Forcing Stem Cells to Behave: A Biophysical Perspective of the Cellular Microenvironment
نویسندگان
چکیده
منابع مشابه
Forcing stem cells to behave: a biophysical perspective of the cellular microenvironment.
Physical factors in the local cellular microenvironment, including cell shape and geometry, matrix mechanics, external mechanical forces, and nanotopographical features of the extracellular matrix, can all have strong influences on regulating stem cell fate. Stem cells sense and respond to these insoluble biophysical signals through integrin-mediated adhesions and the force balance between intr...
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ژورنال
عنوان ژورنال: Annual Review of Biophysics
سال: 2012
ISSN: 1936-122X,1936-1238
DOI: 10.1146/annurev-biophys-042910-155306